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The Supreme Court of Pennsylvania(WASHINGTON) -- The U.S. Supreme Court denied a GOP-led request to hold off on using a new House map for the state of Pennsylvania, meaning candidates — including Republican Rick Saccone and Democrat Conor Lamb lawmakers who recently faced off in a tough battle — in the state will run in new districts this November.

The move is a blow to Republican hopes and a boost to Democratic chances of retaking control of the House of Representatives.

It is the second time on Monday Republicans received a judicial blow from the courts. Earlier, a three-judge panel in Pennsylvania upheld the state’s new congressional map.

The Supreme Court announced, "the application for stay presented to Justice Alito and by him referred to the Court is denied."

There are few legal options left for Republicans in the state. The filing deadline for House candidates is tomorrow.

Republicans in the state had filed for a stay against the new map, which was drawn by the state Supreme Court after the Democratic governor and GOP-controlled state legislature could not come to terms on a new one.

The GOP took two legal routes — one before the U.S. Supreme Court and the other before the federal panel.

They lost on both.

Democrats are expected to pick up three to five House seats under the new map, according to estimates by election experts, which would help them on their way to the 24 seats they need to retake control of the lower chamber of Congress.

The filing deadline for House candidates in Pennsylvania is Tuesday.

The three-judge panel ruled that the Republicans had no standing to make their argument. The court also noted that “because fundamental principles of Constitutional standing and judicial restraint prohibit us from exercising jurisdiction, we have no authority to take any action other than to dismiss” the request.

Republicans can appeal the ruling. That appeal could go to the U.S. Supreme Court.

In January, the Pennsylvania Supreme Court ordered a new House map drawn, citing gerrymandered districts that favored Republicans. The GOP has been fighting the court order ever since and the U.S. Supreme Court denied an early request to put a stay on the map.

Republicans currently hold 12 of the state's 18 congressional districts, while Democrats control just five. The special election last week for Pennsylvania’s 18th Congressional District was held under the old map.

Several GOP lawmakers found their House districts dramatically affected by the new map, including Rep. Ryan Costello, who is considering retirement, several state and national officials in GOP politics told ABC News.

His 6th Congressional District was transformed from one that Hillary Clinton won by one point in 2016 to one she would have won by nine points.

Costello has not said he is retiring and his office and campaign did not respond to ABC News' multiple requests for comment.

Pennsylvania’s House delegation took a big hit in Republican members this year.

GOP Rep. Tim Murphy resigned after a scandal. Rep. Lou Barletta is running for Senate. And Reps. Bill Shuster, Charlie Dent and Patrick Meehan are retiring.

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ABC News(ARLINGTON, Tenn.) -- Ten-year-old Eli O’Bryan gets companionship from his canine friend, Einstein, plus a lot more.

The black labrador helps to keep Eli healthy.

Eli was diagnosed at 4 years old with type 1 diabetes, a disease formerly called juvenile diabetes in which the body does not produce insulin.

Einstein is trained as a medical-service dog to detect when Eli’s blood sugar spikes or crashes, and to signal -- with a bark or by placing a paw on Eli -- when Eli and his family need to check his blood-sugar levels.

Before Eli got the dog, he had to wear a sensor that would monitor his blood sugar throughout the day, which he said was awful.

“[The sensor] was stuck in my leg with a giant needle and it hurt so much,” said Eli. “It beeped all the time and it malfunctioned.”

But no longer.

“Now we have Einstein,” Eli said.

A living dog over a technological device

The sensor Eli wore before Einstein was not only uncomfortable, it interrupted his education, sometimes beeping as many 12 times a day during school.

“He wore a pump all the time, he wore a sensor all the time," Amy O’Bryan, Eli’s mother, told ABC News. "We tracked him with an app through his sensor because he's so brittle that he has to be constantly monitored for him to stay functioning.”

But one of the worst things about the sensor is that it gave Eli more control over his blood-sugar levels, which meant he could hurt himself.

A mother's fear

“The scariest for Eli is when he was in fourth grade, he very calmly told me that he didn't want to live anymore,” O'Bryan said. “And to hear that as a mom and for him to be so casual about it, it was just matter of fact.”

Amy feared that Eli could harm himself with the devices and medicine he used to maintain his blood-sugar levels.

So she sought an alternative.

"That's really what started our journey with Einstein," O'Bryan said. "Not only was he suicidal, but he also wore a device on him 24-7 that would have made it very easy for him to end his life."

Amy reached out to CARES Inc., a non-profit based in Concordia, Kansas, that trains service dogs.

The organization works with a prison system that uses the dog training as a work program for the prisoners. And then, the dogs are sent to families to get used to being in a home and school setting.

A dog’s expert nose is what allows Einstein to be trained to pick up on Eli’s blood-sugar changes.

“They say it's actually one of the hardest things to train a dog to do because it's not a constant smell,” said Amy.

The waiting list for dogs from the organization is so long that Eli's family had to wait almost three years from when his mother first inquired before he was approved to get a dog. Even then, it wasn’t a guarantee.

“Eli has to certify that he can handle him in public,” explained Amy about the process of getting to keep Einstein after a week of training and bonding at the Kansas organization. “They have to show that they can handle them in restaurants or social situations …[Eli] was really nervous, ... we didn't want to leave without Einstein from Kansas.”

Eli and Einstein now

In October 2017, the O’Bryan family welcomed Einstein into their home, and Amy considers him another one of her children now.

“It helps having a dog,” said Eli. “Just in general, even if it's not a service dog. Just feels like having a best friend.”

Now, Einstein goes with Eli almost everywhere from school to band practice. The lab knows when it is time to be serious and work, but when the vest comes off, Einstein acts like the 2-year-old pup that he is.

”It's greatly impacted our life,” said Amy. “Just his quality of life, that he doesn't have to wear the sensor, I think it's helped me be more confident that Eli is independent and he can handle it.”

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J. Countess/Getty Images(NEW YORK) -- Time's Up, an advocacy and legal-defense group fighting sexual harassment in Hollywood and beyond, wants New York Gov. Andrew Cuomo to investigate why a prominent prosecutor decided against prosecuting Harvey Weinstein in 2015, two years before dozens of allegations of sexual misconduct and assault against the producer became public.

The open letter, which was exclusively obtained and published by New York magazine's The Cut, calls on Cuomo to "launch an independent investigation of the New York County District Attorney, Cyrus Vance, and the office of the District Attorney to determine the facts related to the decision not to prosecute Harvey Weinstein for sexual abuse crimes against one of his accusers, Ambra Battilana [Gutierrez]."

Gutierrez, a Filipina-Italian model, got Weinstein on audio in March 2015 allegedly admitting to groping her, according to a New York magazine article referenced in the Time's Up letter. The audio recording was part of a sting operation led by the New York Police Department.

On the tape, Weinstein tries to convince her to come into his room, and only after almost two minutes of back-and-forth in the hallway does Weinstein finally end his efforts to get her to stay, New York magazine reported.

Time's Up's open letter to the New York governor focuses on a New York magazine's report suggesting that the district attorney's office may have mishandled the case against Weinstein at the time.

"Reports that District Attorney Cyrus Vance could have been improperly influenced by Mr. Weinstein and/or his representatives, and that senior officials within the DA’s office may have sought to intimidate Battilana are particularly disturbing and merit investigation," the letter said.

"Similarly, reports that the New York Police Department chose to isolate Battilana from Vance’s staff because they feared his office was actively working to discredit her story demand immediate scrutiny," the letter continued.

Gutierrez said previously about her experience with Weinstein, “There were two years where I lost a lot in my life, but I wanted to help others. I’m happy now no one will suffer anymore.”

ABC News reached out to Gutierrez on Monday, but didn't immediately hear back.

The district attorney’s office told ABC News that the New York magazine article “bears little resemblance to the facts.”

“The Manhattan DA's pioneering sex crimes unit – the first of its kind in the country – has been a national leader in the investigation and prosecution of sexual assaults committed by perpetrators of all backgrounds since the 1970s,” the statement continued. “The idea that our office would shrink from the challenge of prosecuting a powerful man is belied by our daily work and unparalleled record of success on behalf of sexual assault survivors.”

The statement went on to describe the different roles of prosecutors and police, concluding that because of current, active investigations of Weinstein, the prosecutor’s office can’t comment further.

ABC News also reached out to representatives for Gov. Cuomo and the NYPD but didn’t immediately hear back.

Weinstein's lawyer, Ben Brafman, in a statement to ABC News slammed the New York magazine report on Gutierrez.

"We are stunned that NY Magazine chose to report on the claim" by Gutierrez against Weinstein without noting that in a sworn affidavit she 'stated in substance that her complaint against Harvey was the result of a misunderstanding and that her decision to report the incident to the police, was attributed by her to 'bad advice' she received," Brafman said in his statement.

The NYPD said the 2015 case against Weinstein was never prosecuted, New York magazine reported.

And according to the New Yorker magazine, after the district attorney’s office decided not to press charges, Gutierrez "signed a highly restrictive nondisclosure agreement" with Weinstein in addition to the affidavit.

Time's Up's letter said that if Weinstein had been successfully prosecuted in 2015, other women might have been spared his alleged sexual misconduct.

"Arguably his continued victimization of others could have been avoided," the letter said.

Weinstein, 66, has been accused by dozens of women of sexual misconduct, including rape. Though the former movie mogul has apologized for his behavior and sought professional help, a spokeswoman for him has told ABC News that "any allegations of nonconsensual sex are unequivocally denied by Mr. Weinstein."

Following publicity on the allegations, Weinstein was fired from The Weinstein Company, banned from the Producer's Guild of America and expelled from the Academy of Motion Picture Arts and Sciences.

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Uber(TEMPE, Ariz.) -- A self-driving Uber car hit and killed a pedestrian Sunday night in Tempe, Arizona, police said, in what appears to be the first case of a pedestrian death caused by an autonomous vehicle.

The vehicle was in "autonomous mode at the time of the collision, with a vehicle operator behind the wheel," Tempe police said in a statement.

The female pedestrian, identified as 49-year-old Elaine Herzberg, was walking her bicycle across the street outside the crosswalk when she was struck, police said, adding that an investigation is ongoing.

She died of her injuries at a hospital.

There were no passengers in the Uber vehicle.

In a statement to ABC News, Uber said, "Our hearts go out to the victim’s family. We are fully cooperating with local authorities in their investigation of this incident."

In the wake of the crash, Uber has suspended its self-driving operations in San Francisco, Pittsburgh, Phoenix and Toronto, the ridesharing service said.

Editor's note: An earlier version of this story misidentified the women. She was walking her bike across the street when hit, police said.

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Cindy Ord/Getty Images for We Stand UnitedAs one of the stars of Sex & the City, Cynthia Nixon helped us all visualize what it must be like to live in New York City. Now she's running for governor of New York state.

In a video announcing her campaign, Nixon says, "I love New York. I’ve never lived anywhere else. But something has to change. We want our government to work again, on healthcare, ending mass incarceration, fixing our broken subway."

She continues. "We are sick of politicians who care more about headlines and power than they do about us. It can’t just be business as usual anymore.”

Nixon is challenging the incumbent, Andrew Cuomo, a Democrat who is seeking a third term. Nixon feels that, among other things, Cuomo has failed to improve New York City's mass transit system and push through progressive legislation. She also accuses Cuomo of allowing New York to become "the most unequal state in the country" when it comes to income.

Nixon herself has been politically involved for 17 years, fighting for education funding, marriage equality, women's reproductive rights and more. She plans to travel across the state in the coming weeks to talk with voters.

Should Nixon win, she'd be New York's first female governor, as well as its first LGBTQ governor.

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Subscribe To This Feed, Tenn.) -- The two accused killers of NBA player Lorenzen Wright -- including his former wife -- are set to appear in court together for the first time today for allegedly shooting the athlete nearly eight years ago.

Wright's ex-wife, Sherra Wright, is accused of conspiring with Billy Turner to fatally shoot the 34-year-old basketball player in July 2010, the Shelby County District Attorney's Office in Tennessee said.

Lorenzen and Sherra Wright had filed for divorce in May 2009, according to Shelby County courts.

Lorenzen Wright, a Memphis native, was last seen alive leaving his ex-wife's home in Collierville, Tennessee, on July 18, 2010, the district attorney's office said. Early the next morning, a 911 call was made from his cellphone, but the call was interrupted by the sound of gunfire, the district attorney's office said.

A little more than a week later, on July 28, 2010, the NBA player's body was found in a field, shot several times, the district attorney's office said.

The case went unsolved for years.

Then last November, the alleged murder weapon was found in a lake near Walnut, Mississippi, prosecutors said.

Turner was arrested first, indicted Dec. 5, 2017, on first-degree murder charges.

Sherra Wright's arrest and additional charges for Turner were announced by the district attorney's office later that month: They were both indicted by a Shelby County grand jury on charges of first-degree premeditated murder, conspiracy to commit first-degree murder and attempted first-degree murder.

They have pleaded not guilty, according to the Memphis Commercial Appeal.

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ABC News(LONDON) -- Inspectors from the Organization for the Prohibition of Chemical Weapons (OPCW) are arriving in the U.K. to assess samples of the nerve agent used in the attack against former Russian double-agent Sergei Skripal and his daughter earlier this month.

The OPCW team will study the substance at the military research facility Porton Down, which is located just outside the city of Salisbury, where the attack took place.

The team will also meet with detectives leading the investigation into the poisoning attack.

The British government invited the delegation from the Hague, where the monitoring body is based, to carry out an independent study to identify the substance used in the attack.

U.K. officials believe the Skripals were exposed to a military-grade, Soviet-era nerve agent developed by the Russians.

On Sunday ABC News revealed that intelligence officials believe the substance is a “dusty” organophosphate akin to the Novichok chemicals, and may have been administered through the car’s ventilation system.

The intelligence officials told ABC News up to 38 individuals in Salisbury were affected by the nerve agent but the full impact is still being assessed and more victims sickened by the agent are expected to be identified.

It will be weeks before the OPCW announces the results of its tests.

U.K. Foreign Secretary Boris Johnson has accused Russia of stockpiling the nerve agent over the last decade. Johnson also dismissed a suggestion from Russia's ambassador to the E.U. that the agent may have come from a U.K. laboratory in Porton Down.

The British government announced sanctions against Russia last week, expelling 23 diplomats they have identified as undercover spies, as well as announcing new measures to sanction individuals, bolster counterterrorism efforts and increase funding to Porton Down.

The Kremlin, which has condemned the British accusations as “nonsense,” retaliated by expelling the same number of British officials based in Russia.

E.U. foreign ministers in Brussels asserted their solidarity with the U.K. over the incident. A statement from the bloc called on Russia to "address urgently the questions raised by the UK and the international community and to provide immediate, full and complete disclosure of its Novichok programme to the Organisation for the Prohibition of Chemical Weapons."

The statement did not explicitly accuse Russia of responsibility, dampening British hopes of a more muscular E.U. response to the crisis.

Russian President Vladimir Putin, who on Sunday was re-elected to another term, said "it's complete nonsense to imagine that anyone in Russia could resort to such tricks ahead of the presidential elections and World Cup."

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